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hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model

  • Time:2017年
  • Journal:International Journal of COPD
  • Disease Model:Hydrogen inhalatio
  • Corresponding Author:Xiaoyu liu, Cuiqing Ma, Xiaoyu Wang, Wenjing Wang, Zhu Li, Xiansheng Wang, Pengyu Wang, Wuzhuang sun, Baojian Xue
  • Corresponding Unit:Hebei Medical College Dai-ichi Clinic
  • Experimental Subject:Rats
  • Way of Hydrogen Administration:Hydrogen inhalation
  • Dosage:21% O2 + 2% H2 + 77% N2, 21% O2 +22% H2, 21% O2 +41.6% H2
  • Duration:1h each time, and more than 4 hours another 1h, for a total of 4 months
Main Result

These results suggest that hydrogen inhalation slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Higher concentrations of hydrogen may represent a more effective way for the rat model.