Ascleway Papers
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Effects of inhaling high concentrations hydrogen gas on neuronal apoptosis and the expression of apoptosis related proteins in the cortical region of rats with cerebral ischemia - reperfusion injury.

  • Time:2017年
  • Journal:Guangdong Medical Journal
  • Disease Model:Cerebral ischemia-reperfusion injury
  • Corresponding Author:XIA Yuning, LI Xuemei, YUAN Nannan, ZHANG Xinlei, TAN Yongxing
  • Corresponding Unit:Second War Medical University
  • Experimental Subject:Rats
  • Way of Hydrogen Administration:hydrogen inhalatio
  • Dosage:67% H2- 33%O2 mixture inhalation
  • Duration:2h
Main Result

High concentration hydrogen during reperfusion can protect the I/R rats by reducing the size of cerebral infarction, ameliorating the neurological deficit and neuron apoptosis, and which may be related with upregulating Bcl-2 and downregulating Bax.

Classification of Disease:Liver disease